A little-known fact about "Hot in Herre" is that the song samples Chuck Brown's 1979 go-go hit "Bustin' Loose." The go-go music genre, which originated in Washington, D.C., features a distinct, funky beat that heavily influenced the rhythm of "Hot in Herre." This sample played a significant role in giving the song its infectious groove, blending hip-hop with go-go’s energetic feel, which helped it become such a massive hit. Additionally, the song's iconic hook, "It's gettin' hot in here, so take off all your clothes," was inspired by a conversation Nelly had with a friend about how hot it was during a night out.